Complications and prostate cancer diagnosis rate of TRUS prostate biopsies using 16 and 18G needles by Clavien scoring



We aimed to compare the 18 and 16-Gauge (G) needles used in transrectal ultrasonography (TRUS)-guided needle biopsy for cancer detection rates and complications using the Clavien Scoring System.

Materials and methods

The 80 patients who were included in the study were randomized and divided into two groups. Group 1 (n = 36) had a TRUS-guided prostate biopsy with an 18G needle and Group 2 had a 16G needle (n = 44). The hematuria, bleeding assessment, and infection events were evaluated on a daily basis. These complications were graded according to the Clavien Scoring.


In Group 1, only five (13%) patients were diagnosed with prostate cancer, and three patients were reported to have atypical small acinar proliferation (ASAP). In Group 2, 16 (36%) patients were diagnosed with prostate cancer and one patient was reported to have ASAP. The difference in the prostate cancer detection rate between the groups was statistically significant. According to the Clavien grading system, the complications were at the Grade 1 level in 25 people in Group 1 in 29 people in Group 2. Grade 2 level complications were not observed in either group. While one person was Grade 3 in Group 1, two people in Group 2 had this rate. There were no significant differences between the groups.


We found that cancer detection rate increased by increasing the thickness of the needle used in TRUS-guided prostate biopsy without any increase in the complications.

In press - Corrected proof




Serkan Ozcan, Mehmet Akif Diri, Murat Bagcioglu, Tolga Karakan, Arif Aydın

Article History


Financial support: The authors declare that this study received no financial support.
Conflict of interest: No conflicts of interest are declared by the authors.

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  • Urology Department, Artvin State Hospital, Artvin - Turkey
  • Urology Department, Ankara Training and Research Hospital, Ankara - Turkey
  • Urology Department, Faculty of Medicine, Kafkas University, Kars - Turkey
  • Urology Department, Faculty of Medicine, Necmettin Erbakan University, Konya - Turkey

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